Dried Blood Spot Sampling to Assess Rifampicin Exposure and Treatment Outcomes among Native and Non-Native Tuberculosis Patients in Paraguay: An Exploratory Study

• Main Authors: Samiksha Ghimire (Author), Gladys Molinas (Author), Arturo Battaglia (Author), Nilza Martinez (Author), Luis Gómez Paciello (Author), Sarita Aguirre (Author), Jan-Willem C. Alffenaar (Author), Marieke G. G. Sturkenboom (Author), Cecile Magis-Escurra (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to evaluate the difference in drug exposure of rifampicin in native versus non-native Paraguayan populations using dried blood spots (DBS) samples collected utilizing a limited sampling strategy. This was a prospective pharmacokinetic study that enrolled hospitalized tuberc...