Celastrus orbiculatus Thunb. extracts and celastrol alleviate NAFLD by preserving mitochondrial function through activating the FGF21/AMPK/PGC-1α pathway

• 主要な著者: Junli Xue (著者), Yunchao Liu (著者), Boyan Liu (著者), Xiubin Jia (著者), Xinsheng Fang (著者), Shucun Qin (著者), Ying Zhang (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

ObjectiveNon-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disease globally, characterized by the accumulation of lipids, oxidative stress, and mitochondrial dysfunction in the liver. Celastrus orbiculatus Thunb. (COT) and its active compound celastrol (CEL) have demonstrated an...