Celastrus orbiculatus Thunb. extracts and celastrol alleviate NAFLD by preserving mitochondrial function through activating the FGF21/AMPK/PGC-1α pathway

Celastrus orbiculatus Thunb. extracts and celastrol alleviate NAFLD by preserving mitochondrial function through activating the FGF21/AMPK/PGC-1α pathway

ObjectiveNon-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disease globally, characterized by the accumulation of lipids, oxidative stress, and mitochondrial dysfunction in the liver. Celastrus orbiculatus Thunb. (COT) and its active compound celastrol (CEL) have demonstrated an...

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Main Authors: Junli Xue (Author), Yunchao Liu (Author), Boyan Liu (Author), Xiubin Jia (Author), Xinsheng Fang (Author), Shucun Qin (Author), Ying Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
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