Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection.

• Príomhchruthaitheoirí: Didier Bakajika (Údar), Eric M Kanza (Údar), Nicholas O Opoku (Údar), Hayford M Howard (Údar), Germain L Mambandu (Údar), Amos Nyathirombo (Údar), Maurice M Nigo (Údar), Kambale Kasonia Kennedy (Údar), Safari L Masembe (Údar), Mupenzi Mumbere (Údar), Kambale Kataliko (Údar), Kpehe M Bolay (Údar), Simon K Attah (Údar), George Olipoh (Údar), Sampson Asare (Údar), Michel Vaillant (Údar), Christine M Halleux (Údar), Annette C Kuesel (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Public Library of Science (PLoS), 2022-04-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

<h4>Background</h4>Our study in CDTI-naïve areas in Nord Kivu and Ituri (Democratic Republic of the Congo, DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single 8 mg moxidectin dose reduced skin microfilariae density (microfilariae/mg skin, SmfD) better and for l...