Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection.

• Main Authors: Didier Bakajika (Author), Eric M Kanza (Author), Nicholas O Opoku (Author), Hayford M Howard (Author), Germain L Mambandu (Author), Amos Nyathirombo (Author), Maurice M Nigo (Author), Kambale Kasonia Kennedy (Author), Safari L Masembe (Author), Mupenzi Mumbere (Author), Kambale Kataliko (Author), Kpehe M Bolay (Author), Simon K Attah (Author), George Olipoh (Author), Sampson Asare (Author), Michel Vaillant (Author), Christine M Halleux (Author), Annette C Kuesel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Our study in CDTI-naïve areas in Nord Kivu and Ituri (Democratic Republic of the Congo, DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single 8 mg moxidectin dose reduced skin microfilariae density (microfilariae/mg skin, SmfD) better and for l...