Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo.

• Main Authors: Patient Pyana Pati (Author), Nick Van Reet (Author), Dieudonné Mumba Ngoyi (Author), Ipos Ngay Lukusa (Author), Stomy Karhemere Bin Shamamba (Author), Philippe Büscher (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sleeping sickness caused by Trypanosoma brucei (T.b.) gambiense constitutes a serious health problem in sub-Sahara Africa. In some foci, alarmingly high relapse rates were observed in patients treated with melarsoprol, which used to be the first line treatment for patients in the neurological diseas...