Structural Adaptation of the Single-Stranded DNA-Binding Protein C-Terminal to DNA Metabolizing Partners Guides Inhibitor Design

Structural Adaptation of the Single-Stranded DNA-Binding Protein C-Terminal to DNA Metabolizing Partners Guides Inhibitor Design

Single-stranded DNA-binding protein (SSB) is a bacterial interaction hub and an appealing target for antimicrobial therapy. Understanding the structural adaptation of the disordered SSB C-terminus (SSB-Ct) to DNA metabolizing enzymes (e.g., ExoI and RecO) is essential for designing high-affinity SSB...

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Main Authors: Attila Tököli (Author), Brigitta Bodnár (Author), Ferenc Bogár (Author), Gábor Paragi (Author), Anasztázia Hetényi (Author), Éva Bartus (Author), Edit Wéber (Author), Zsófia Hegedüs (Author), Zoltán Szabó (Author), Gábor Kecskeméti (Author), Gerda Szakonyi (Author), Tamás A. Martinek (Author)
Format: Book
Published: MDPI AG, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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