Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition

Abstract Background House dust mite (HDM) inhalation can cause airway epithelial damage which is implicated in the process of airway inflammation in asthma. High mobility group box 1 (HMGB1) is critically required for cellular damage and apoptosis as an important endogenous danger signal. Recently,...

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Main Authors: Meixuan Liu (Author), Jingjing Lu (Author), Qian Zhang (Author), Yunxuan Zhang (Author), Zhongliang Guo (Author)
Format: Book
Published: BMC, 2021-02-01T00:00:00Z.
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