Sustained and Targeted Delivery of Self-Assembled Doxorubicin Nonapeptides Using pH-Responsive Hydrogels for Osteosarcoma Chemotherapy

• Main Authors: Jie Zhu (Author), Rui Gao (Author), Zhongshi Wang (Author), Zhiming Cheng (Author), Zhonghua Xu (Author), Zaiyang Liu (Author), Yiqun Wu (Author), Min Wang (Author), Yuan Zhang (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While chemotherapeutic agents have particularly potent effects in many types of cancer, their clinical applications are still far from satisfactory due to off-target drug exposure, chemotherapy resistance, and adverse effects, especially in osteosarcoma. Therefore, it is clinically promising to cons...