Pardaxin Activates Excessive Mitophagy and Mitochondria-Mediated Apoptosis in Human Ovarian Cancer by Inducing Reactive Oxygen Species

• Main Authors: Yen-Po Chen (Author), Po-Chang Shih (Author), Chien-Wei Feng (Author), Chang-Cheng Wu (Author), Kuan-Hao Tsui (Author), You-Hsien Lin (Author), Hsiao-Mei Kuo (Author), Zhi-Hong Wen (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most ovarian cancer (OC) patients are diagnosed with stage III or higher disease, resulting in a poor prognosis. Currently, paclitaxel combined with carboplatin shows the best treatment outcome for OC. However, no effective drug is available for patients that do not respond to treatment; thus, new d...