Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promising Anticancer and Antimicrobial Activity

Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promising Anticancer and Antimicrobial Activity

The 1-(4-acetamidophenyl)-5-oxopyrrolidine carboxylic acid was applied for synthesizing derivatives bearing azole, diazole, and hydrazone moieties in the molecule. Modification of an acetamide fragment to the free amino group afforded compounds with two functional groups, which enabled to provide a...

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Main Authors: Karolina Kairytė (Author), Birutė Grybaitė (Author), Rita Vaickelionienė (Author), Birutė Sapijanskaitė-Banevič (Author), Povilas Kavaliauskas (Author), Vytautas Mickevičius (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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