Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease.
The protozoan parasite Trypanosoma cruzi is able to target the thymus and induce alterations of the thymic microenvironmental and lymphoid compartments. Acute infection results in severe atrophy of the organ and early release of immature thymocytes into the periphery. To date, the pathophysiological...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Book |
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Public Library of Science (PLoS),
2014-10-01T00:00:00Z.
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