Quercetin Decreases Th17 Production by Down-Regulation of MAPK- TLR4 Signaling Pathway on T Cells in Dental Pulpitis

• Main Authors: Ali Mahmoud Hashemi (Author), Shiva Solahaye Kahnamouii (Author), Hassan Agajani (Author), Khalil Frozannia (Author), Alireza Pournasrollah (Author), Rasoul Sadeg (Author), Heidarali Esmaeeli (Author), Yosef Gadimi (Author), Ebrahim Razmpa (Author)
• Format: Book
• Published: Shiraz University of Medical Sciences, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Statement of the Problem: Quercetin is a pharmacological flavonoid that can inhibit high mobility group box1 (HMGB1) protein, a non-histone nuclear protein that is implicated in inflammation. Th17 cells are important cells in the pathogenesis of inflammation. Pulpitis is the inflammation of dental p...