Peripheral Antinociception by Carbamazepine in an Inflammatory Mechanical Hyperalgesia Model in the Rat: a New Target for Carbamazepine?

• Main Authors: Sonja Vučković (Author), Maja Tomić (Author), Radica Stepanović-Petrović (Author), Nenad Ugrešić (Author), Milica Prostran (Author), Bogdan Bošković (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: This study investigated whether carbamazepine could produce local peripheral antinociception in a rat model of inflammatory mechanical hyperalgesia, and whether adenosine receptors are involved. Carbamazepine (100 - 1000 nmol/paw) coadministrated with a proinflammatory compound, concanava...