Targeting HMGB1-NFκb Axis and miR-21 by Glycyrrhizin: Role in Amelioration of Corneal Injury in a Mouse Model of Alkali Burn

• Main Authors: Peihong Wang (Author), Peng Hao (Author), Xi Chen (Author), Linghan Li (Author), Yongying Zhou (Author), Xiaohan Zhang (Author), Lin Zhu (Author), Ming Ying (Author), Ruifang Han (Author), Liming Wang (Author), Xuan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Corneal neovascularization (CNV) is a sight-threatening condition usually associated with various inflammatory settings including chemical injury. High mobility group box 1 (HMGB1) is identified as an inflammatory alarmin in diverse tissue damage. Here, we evaluate the expression of HMGB1 and the co...