Dehydroepiandrosterone suppresses human colorectal cancer progression through ER stress-mediated autophagy and apoptosis in a p53-independent manner

• Hauptverfasser: Thi-Huong Nguyen (Verfasst von), Huey-Jiun Ko (Verfasst von), Po-Yu Tsai (Verfasst von), Tai-Shan Cheng (Verfasst von), Thu-Ha Tran (Verfasst von), Ly Hien Doan (Verfasst von), Michael Hsiao (Verfasst von), Peter Mu-Hsin Chang (Verfasst von), Hsiao-Sheng Liu (Verfasst von), Yi-Ren Hong (Verfasst von), Chi-Ying F. Huang (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Colorectal cancer (CRC) is one of the primary contributors to cancer-related fatalities, with up to 80% of advanced CRC cases exhibiting mutations in the p53 gene. Unfortunately, the development of new compounds targeting mutant p53 is quite limited. The anticancer effects of Dehydroepiandrosterone...