Utility of Lymphocyte Transformation Test for Assisting Updated Roussel Uclaf Causality Assessment Method in Drug-Induced Liver Injury: A Case-Control Study

• Main Authors: Amelia Rodríguez (Author), Irene García-García (Author), Lucía Martínez de Soto (Author), Arturo Gómez López De Las Huertas (Author), Alberto M. Borobia (Author), Andrea González-Torbay (Author), Ibtissam Akatbach-Bousaid (Author), Miguel González-Muñoz (Author), Elena Ramírez (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The Roussel Uclaf Causality Assessment Method (RUCAM) is a validated tool for assessing causality in cases of suspected drug-induced liver injury (DILI). However, RUCAM cannot discriminate between concomitant hepatotoxic drugs with the same temporal sequence.Objective: To analyse the uti...