Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

• Hoofdauteurs: Sabine Rutti (Auteur), Caroline Arous (Auteur), Domitille Schvartz (Auteur), Katharina Timper (Auteur), Jean-Charles Sanchez (Auteur), Emmanouil Dermitzakis (Auteur), Marc Y. Donath (Auteur), Philippe A. Halban (Auteur), Karim Bouzakri (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2014-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: We have previously shown the existence of a muscle-pancreas intercommunication axis in which CX3CL1 (fractalkine), a CX3C chemokine produced by skeletal muscle cells, could be implicated. It has recently been shown that the fractalkine system modulates murine β-cell function. However, the...