Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

• Main Authors: Sabine Rutti (Author), Caroline Arous (Author), Domitille Schvartz (Author), Katharina Timper (Author), Jean-Charles Sanchez (Author), Emmanouil Dermitzakis (Author), Marc Y. Donath (Author), Philippe A. Halban (Author), Karim Bouzakri (Author)
• Format: Book
• Published: Elsevier, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: We have previously shown the existence of a muscle-pancreas intercommunication axis in which CX3CL1 (fractalkine), a CX3C chemokine produced by skeletal muscle cells, could be implicated. It has recently been shown that the fractalkine system modulates murine β-cell function. However, the...