Synthesis and Structure-Activity Relationships of New 2-Phenoxybenzamides with Antiplasmodial Activity

• Main Authors: Theresa Hermann (Author), Patrick Hochegger (Author), Johanna Dolensky (Author), Werner Seebacher (Author), Eva-Maria Pf (Author), Robert Saf (Author), Marcel Kaiser (Author), Pascal Mäser (Author), Robert Weis (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The 2-phenoxybenzamide <b>1</b> from the Medicines for Malaria Venture Malaria Box Project has shown promising multi-stage activity against different strains of <i>P. falciparum</i>. It was successfully synthesized via a retrosynthetic approach. Subsequently, twenty-one new d...