Evidence of altered redox homeostasis in trichothiodystrophy

• Main Authors: Valeria Cordone (Author), Anna Guiotto (Author), Vivian Bucay (Author), Alessandra Pecorelli (Author), Giuseppe Valacchi (Author)
• Format: Book
• Published: Bioscientifica, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Trichothiodystrophy (TTD) is a rare hereditary disease whose prominent feature is brittle hair. Additional clinical signs are physical and neurodevelopmental abnormalities and in about half of the cases hypersensitivity to UV radiation. Although the mutations involved in this condition ha...