Study Protocol for Preventing Early-Onset Pneumonia in Young Children Through Maternal Immunisation: A Multi-Centre Randomised Controlled Trial (PneuMatters)

• Main Authors: Anne B. Chang (Author), Maree Toombs (Author), Mark D. Chatfield (Author), Remai Mitchell (Author), Siew M. Fong (Author), Michael J. Binks (Author), Heidi Smith-Vaughan (Author), Susan J. Pizzutto (Author), Karin Lust (Author), Peter S. Morris (Author), Julie M. Marchant (Author), Stephanie T. Yerkovich (Author), Hannah O'Farrell (Author), Paul J. Torzillo (Author), Carolyn Maclennan (Author), David Simon (Author), Holger W. Unger (Author), Hasthika Ellepola (Author), Jens Odendahl (Author), Helen S. Marshall (Author), Geeta K. Swamy (Author), Keith Grimwood (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Preventing and/or reducing acute lower respiratory infections (ALRIs) in young children will lead to substantial short and long-term clinical benefits. While immunisation with pneumococcal conjugate vaccines (PCV) reduces paediatric ALRIs, its efficacy for reducing infant ALRIs following...