Peptidoglycan-Mediated Bone Marrow Autonomic Neuropathy Impairs Hematopoietic Stem/Progenitor Cells via a NOD1-Dependent Pathway in db/db Mice

• Váldodahkkit: Jing Wu (Dahkki), Binghan Zhang (Dahkki), Shengbing Li (Dahkki), Wenwen Chen (Dahkki), Jinning Mao (Dahkki), Ke Li (Dahkki), Dongfang Liu (Dahkki), Yaqian Duan (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2022-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Impairment of bone marrow-derived hematopoietic stem/progenitor cells (HSPCs) contributes to the progression of vascular complications in subjects with diabetes. Very small amounts of bacterial-derived pathogen-associated molecular patterns (PAMPs) establish the bone marrow cell pool. We hypothesize...