Bioequivalence of two oral formulations of tebipenem pivoxil hydrobromide in healthy subjects

• Main Authors: Vipul K. Gupta (Author), Gina Patel (Author), Leanne Gasink (Author), Floni Bajraktari (Author), Yang Lei (Author), Akash Jain (Author), Praveen Srivastava (Author), Angela K. Talley (Author)
• Format: Book
• Published: Wiley, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tebipenem pivoxil hydrobromide (TBP‐PI‐HBr) is a novel oral carbapenem prodrug of tebipenem (TBP), the active moiety, currently in development for treating serious bacterial infections. This study assessed the bioequivalence (BE) of the clinical trial and registration tablet formulations of...