Catechin-Induced changes in PODXL, DNMTs, and miRNA expression in Nalm6 cells: an integrated in silico and in vitro approach

• Main Authors: Ali Afgar (Author), Alireza Keyhani (Author), Amirreza Afgar (Author), Mohamad Javad Mirzaei-Parsa (Author), Mahdiyeh Ramezani Zadeh Kermani (Author), Masoud Rezaei (Author), Mohammad Ebrahimipour (Author), Ladan Langroudi (Author), Mahla Sattarzadeh Bardsiri (Author), Reza Vahidi (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This study explored the impact of predicted miRNAs on DNA methyltransferases (DNMTs) and the PODXL gene in Nalm6 cells, revealing the significance of these miRNAs in acute lymphocytic leukemia (ALL). Methods A comprehensive approach was adopted, integrating bioinformatic analyses...