Tonic Endocannabinoid Signaling Gates Synaptic Plasticity in Dorsal Raphe Nucleus Serotonin Neurons Through Peroxisome Proliferator-Activated Receptors

• Main Authors: Saida Oubraim (Author), Ruixiang Wang (Author), Kathryn A Hausknecht (Author), Roh-Yu Shen (Author), Samir Haj-Dahmane (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Endocannabinoids (eCBs), which include 2-arachidonoylglycerol (2-AG) and anandamide (AEA) are lipid signaling molecules involved in the regulation of an array of behavioral and physiological functions. Released by postsynaptic neurons, eCBs mediate both phasic and tonic signaling at central synapses...