Targeting Regulatory T Cells for Therapy of Lupus Nephritis

• 主要な著者: Rajkumar Venkatadri (著者), Vikram Sabapathy (著者), Murat Dogan (著者), Rahul Sharma (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Lupus glomerulonephritis (LN) is a complex autoimmune disease characterized by circulating autoantibodies, immune-complex deposition, immune dysregulation and defects in regulatory T cell (Tregs). Treatment options rely on general immunosuppressants and steroids that have serious side effects. Appro...