Regulation of S100A8/A9 (Calprotectin) Binding to Tumor Cells by Zinc Ion and Its Implication for Apoptosis-Inducing Activity

• Päätekijät: Yuichi Nakatani (Tekijä), Masatoshi Yamazaki (Tekijä), Walter J. Chazin (Tekijä), Satoru Yui (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Hindawi Limited, 2005-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

S100A8/A9 (calprotectin), which is released by neutrophils under inflammatory conditions, has the capacity to induce apoptosis in various cells. We previously reported that S100A8/A9 induces apoptosis of EL-4 lymphoma cells via the uptake of extracellular zinc in a manner similar to DTPA, a membrane...