Metastatic and recurrent adrenocortical cancer is not defined by its genomic landscape

• Main Authors: Tito Fojo (Author), Lyn Huff (Author), Thomas Litman (Author), Kate Im (Author), Maureen Edgerly (Author), Jaydira del Rivero (Author), Stefania Pittaluga (Author), Maria Merino (Author), Susan E. Bates (Author), Michael Dean (Author)
• פורמט: ספר
• יצא לאור: BMC, 2020-11-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background Adrenocortical carcinoma (ACC) is a rare, often-aggressive neoplasm of the adrenal cortex, with a 14-17 month median overall survival. We asked whether tumors from patients with advanced or metastatic ACC would offer clues as to putative genes that might have critical roles in di...