Akt Is a Molecular Target for Signal Transduction Therapy in Brain Ischemic Insult
Growth factors including insulin-like growth factor-1 (IGF-1) promote cell survival in ischemic brain injury. Stimulation of IGF-1 receptor coupled with tyrosine kinase activates phosphatidylinositol 3-kinase and subsequently, protein kinase B (Akt) in hippocampal neurons. Here we introduce a new ap...
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| Main Authors: | , |
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| Format: | Book |
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Elsevier,
2003-01-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |