Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism

• Main Authors: Zhao Cui (Author), Huajing Wang (Author), Shuo Li (Author), Tingting Qin (Author), Hang Shi (Author), Ji Ma (Author), Lanfang Li (Author), Guihua Yu (Author), Tingliang Jiang (Author), Canghai Li (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although sorafenib (Sora) shows improved efficacy in clinical liver cancer therapy, its therapeutic efficacy is still greatly limited due to side effects as well as drug resistance. Thus new drug intervention strategies are imperative. Our research showed the combined application of Dihydroartemisin...