The regulatory mechanisms and inhibitors of isocitrate dehydrogenase 1 in cancer

• Main Authors: Yang Liu (Author), Wei Xu (Author), Mingxue Li (Author), Yueying Yang (Author), Dejuan Sun (Author), Lidian Chen (Author), Hua Li (Author), Lixia Chen (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reprogramming of energy metabolism is one of the basic characteristics of cancer and has been proved to be an important cancer treatment strategy. Isocitrate dehydrogenases (IDHs) are a class of key proteins in energy metabolism, including IDH1, IDH2, and IDH3, which are involved in the oxidative de...