The regulatory mechanisms and inhibitors of isocitrate dehydrogenase 1 in cancer

• मुख्य लेखकों: Yang Liu (लेखक), Wei Xu (लेखक), Mingxue Li (लेखक), Yueying Yang (लेखक), Dejuan Sun (लेखक), Lidian Chen (लेखक), Hua Li (लेखक), Lixia Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Reprogramming of energy metabolism is one of the basic characteristics of cancer and has been proved to be an important cancer treatment strategy. Isocitrate dehydrogenases (IDHs) are a class of key proteins in energy metabolism, including IDH1, IDH2, and IDH3, which are involved in the oxidative de...