Declining antibody levels to Trypanosoma cruzi correlate with polymerase chain reaction positivity and electrocardiographic changes in a retrospective cohort of untreated Brazilian blood donors.

• Principais autores: Lewis F Buss (Autor), Léa Campos de Oliveira-da Silva (Autor), Carlos H V Moreira (Autor), Erika R Manuli (Autor), Flavia C Sales (Autor), Ingra Morales (Autor), Clara Di Germanio (Autor), Cesar de Almeida-Neto (Autor), Sonia Bakkour (Autor), Paul Constable (Autor), Marcelo M Pinto-Filho (Autor), Antonio L Ribeiro (Autor), Michael Busch (Autor), Ester C Sabino (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2020-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<h4>Background</h4>Although infection with Trypanosoma cruzi is thought to be lifelong, less than half of those infected develop cardiomyopathy, suggesting greater parasite control or even clearance. Antibody levels appear to correlate with T. cruzi (antigen) load. We test the associatio...