Low Intraprostatic DHT Promotes the Infiltration of CD8+ T Cells in BPH Tissues via Modulation of CCL5 Secretion

• Main Authors: Yu Fan (Author), Shuai Hu (Author), Jie Liu (Author), Fei Xiao (Author), Xin Li (Author), Wei Yu (Author), Yun Cui (Author), Mengkui Sun (Author), Tianjing Lv (Author), Qun He (Author), Jie Jin (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinical studies suggested thatandrogen might be associated with infiltrating T cells in prostate of benign prostatic hyperplasia (BPH) patients, but detail of T-cell subset and mechanism still remained unclear. The present study tested the hypothesis that intraprostatic 5α-dihydrotestosterone (DHT)...