Evaluation of Brain Targeting and Antipsychotic Activity of Nasally Administrated Ziprasidone Lipid-Polymer Hybrid Nanocarriers

• मुख्य लेखकों: Hadel A. Abo El-Enin (लेखक), Alaa S. Tulbah (लेखक), Hany W. Darwish (लेखक), Rania Salama (लेखक), Ibrahim A. Naguib (लेखक), Heba A. Yassin (लेखक), Hend Mohamed Abdel-Bar (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The feasibility of using lipid-polymer hybrid (LPH) nanocarriers as a potential platform for the intranasal delivery of ziprasidone (ZP), a second-generation antipsychotic, was explored. Different ZP-loaded LPH composed of a PLGA core and cholesterol-lecithin lipid coat were prepared using a single...