In Vitro Stability and Pharmacokinetic Study of Pedunculoside and Its Beta-CD Polymer Inclusion Complex

• Príomhchruthaitheoirí: Liang Wu (Údar), Danfeng Li (Údar), Peijing Wang (Údar), Linling Dong (Údar), Wang Zhang (Údar), Jianjun Xu (Údar), Xiaoliang Jin (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2024-04-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Pedunculoside, a triterpene saponin derived from various <i>Ilex</i> species, holds potential as a treatment for cardiovascular diseases. However, its clinical application is hindered by poor bioavailability, rapid elimination, and extensive intestinal metabolism to rotundic acid. To add...