Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats

Tadalafil is a cytochrome P450 (CYP) 3A4 substrate. Because there are few data on drug-drug interactions, it is advisable to take sufficient consideration when co-administering tadalafil with CYP3A4 inducers or inhibitors. This study was conducted to assess the effect of ticagrelor, a CYP3A4 inhibit...

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Bibliographic Details
Main Authors: Young-Guk Na (Author), Jin-Ju Byeon (Author), Hyun Wook Huh (Author), Min-Ki Kim (Author), Young G. Shin (Author), Hong-Ki Lee (Author), Cheong-Weon Cho (Author)
Format: Book
Published: MDPI AG, 2019-07-01T00:00:00Z.
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