Canagliflozin alleviates valproic acid-induced autism in rat pups: Role of PTEN/PDK/PPAR-γ signaling pathways

• Main Authors: Mariam A. Elgamal (Author), Dina M. Khodeer (Author), Basel A. Abdel-Wahab (Author), Ibrahim Abdel Aziz Ibrahim (Author), Abdullah R. Alzahrani (Author), Yasser M. Moustafa (Author), Azza A. Ali (Author), Norhan M. El-Sayed (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Autism is complex and multifactorial, and is one of the fastest growing neurodevelopmental disorders. Canagliflozin (Cana) is an antidiabetic drug that exhibits neuroprotective properties in various neurodegenerative syndromes. This study investigated the possible protective effect of Cana against t...