Transthyretin Stabilizers and Seeding Inhibitors as Therapies for Amyloid Transthyretin Cardiomyopathy

• Main Authors: Paolo Morfino (Author), Alberto Aimo (Author), Giuseppe Vergaro (Author), Chiara Sanguinetti (Author), Vincenzo Castiglione (Author), Maria Franzini (Author), Marco Alfonso Perrone (Author), Michele Emdin (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transthyretin (TTR) amyloid cardiomyopathy (ATTR-CM) is a progressive and increasingly recognized cause of heart failure which is associated with high mortality and morbidity. ATTR-CM is characterized by the misfolding of TTR monomers and their deposition within the myocardium as amyloid fibrils. Th...