Ultrasound-Responsive Nrf2-Targeting siRNA-Loaded Nanobubbles for Enhancing the Treatment of Melanoma

• Główni autorzy: Monica Argenziano (Autor), Federica Bessone (Autor), Chiara Dianzani (Autor), Marie Angèle Cucci (Autor), Margherita Grattarola (Autor), Stefania Pizzimenti (Autor), Roberta Cavalli (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The siRNA-mediated inhibition of nuclear factor E2-related factor 2 (Nrf2) can be an attractive approach to overcome chemoresistance in various malignant tumors, including melanoma. This work aims at designing a new type of chitosan-shelled nanobubble for the delivery of siRNA against Nrf2 in combin...