Ultrasound-Responsive Nrf2-Targeting siRNA-Loaded Nanobubbles for Enhancing the Treatment of Melanoma

Ultrasound-Responsive Nrf2-Targeting siRNA-Loaded Nanobubbles for Enhancing the Treatment of Melanoma

The siRNA-mediated inhibition of nuclear factor E2-related factor 2 (Nrf2) can be an attractive approach to overcome chemoresistance in various malignant tumors, including melanoma. This work aims at designing a new type of chitosan-shelled nanobubble for the delivery of siRNA against Nrf2 in combin...

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Main Authors: Monica Argenziano (Author), Federica Bessone (Author), Chiara Dianzani (Author), Marie Angèle Cucci (Author), Margherita Grattarola (Author), Stefania Pizzimenti (Author), Roberta Cavalli (Author)
Format: Book
Published: MDPI AG, 2022-01-01T00:00:00Z.
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