The Inflammation in the Cytopathology of Patients With Mucopolysaccharidoses- Immunomodulatory Drugs as an Approach to Therapy

• Main Authors: Anna-Maria Wiesinger (Author), Brian Bigger (Author), Roberto Giugliani (Author), Maurizio Scarpa (Author), Tobias Moser (Author), Christina Lampe (Author), Christoph Kampmann (Author), Florian B. Lagler (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mucopolysaccharidoses (MPS) are a group of lysosomal storage diseases (LSDs), characterized by the accumulation of glycosaminoglycans (GAGs). GAG storage-induced inflammatory processes are a driver of cytopathology in MPS and pharmacological immunomodulation can bring improvements in brain, cartilag...