Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives

Monoclonal antibodies (mAbs), such as infliximab, are important treatment options for different diseases. Immunogenicity is a major risk, resulting in anti-drug antibodies (ADAs), being associated with adverse events and loss of response, influencing long-term outcomes. The development of ADAs again...

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Main Authors: Erin H. Smeijsters (Author), Kim C. M. van der Elst (Author), Amy Visch (Author), Camiel Göbel (Author), Floris C. Loeff (Author), Theo Rispens (Author), Alwin D. R. Huitema (Author), Matthijs van Luin (Author), Mohsin El Amrani (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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