Synthesis and Characterization of Novel 2-Acyl-3-trifluoromethylquinoxaline 1,4-Dioxides as Potential Antimicrobial Agents

• Main Authors: Galina I. Buravchenko (Author), Dmitry A. Maslov (Author), Md Shah Alam (Author), Natalia E. Grammatikova (Author), Svetlana G. Frolova (Author), Aleksey A. Vatlin (Author), Xirong Tian (Author), Ivan V. Ivanov (Author), Olga B. Bekker (Author), Maxim A. Kryakvin (Author), Olga A. Dontsova (Author), Valery N. Danilenko (Author), Tianyu Zhang (Author), Andrey E. Shchekotikhin (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The emergence of drug resistance in pathogens leads to a loss of effectiveness of antimicrobials and complicates the treatment of bacterial infections. Quinoxaline 1,4-dioxides represent a prospective scaffold for search of new compounds with improved chemotherapeutic characteristics. Novel 2-acyl-3...