Positive allosteric modulation of TRPV1 as a novel analgesic mechanism

• Main Authors: Lebovitz Evan E (Author), Keller Jason M (Author), Kominsky Hal (Author), Kaszas Krisztian (Author), Maric Dragan (Author), Iadarola Michael J (Author)
• Format: Book
• Published: SAGE Publishing, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The prevalence of long-term opiate use in treating chronic non-cancer pain is increasing, and prescription opioid abuse and dependence are a major public health concern. To explore alternatives to opioid-based analgesia, the present...