Microenvironment‐induced restoration of cohesive growth associated with focal activation of P‐cadherin expression in lobular breast carcinoma metastatic to the colon

• Main Authors: Malte Gronewold (Author), Isabel Grote (Author), Stephan Bartels (Author), Henriette Christgen (Author), Leonie D Kandt (Author), Maria Jose Brito (Author), Gàbor Cserni (Author), Maximilian E Daemmrich (Author), Franz Fogt (Author), Burkhard M Helmke (Author), Natalie terHoeve (Author), Corinna Lang‐Schwarz (Author), Michael Vieth (Author), Axel Wellmann (Author), Elna Kuehnle (Author), Ulf Kulik (Author), Gesa Riedel (Author), Tanja Reineke‐Plaass (Author), Ulrich Lehmann (Author), Thijs Koorman (Author), Patrick WB Derksen (Author), Hans Kreipe (Author), Matthias Christgen (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Invasive lobular carcinoma (ILC) is a special breast cancer type characterized by noncohesive growth and E‐cadherin loss. Focal activation of P‐cadherin expression in tumor cells that are deficient for E‐cadherin occurs in a subset of ILCs. Switching from an E‐cadherin deficient to P‐cadher...