Benzothiazole Derivatives Endowed with Antiproliferative Activity in Paraganglioma and Pancreatic Cancer Cells: Structure-Activity Relationship Studies and Target Prediction Analysis

• Main Authors: Rosa Amoroso (Author), Laura De Lellis (Author), Rosalba Florio (Author), Nazaret Moreno (Author), Mariangela Agamennone (Author), Barbara De Filippis (Author), Letizia Giampietro (Author), Cristina Maccallini (Author), Inmaculada Fernández (Author), Rocío Recio (Author), Alessandro Cama (Author), Marialuigia Fantacuzzi (Author), Alessandra Ammazzalorso (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The antiproliferative effects played by benzothiazoles in different cancers have aroused the interest for these molecules as promising antitumor agents. In this work, a library of phenylacetamide derivatives containing the benzothiazole nucleus was synthesized and compounds were tested for their ant...