Response to PD-1 inhibitor in SMARCB1‑deficient undifferentiated rectal carcinoma with low TMB, proficient MMR and BRAF V600E mutation: a case report and literature review

Abstract Background Despite major advancements, effective treatment for patients with SMARCB1-deficient cancers has remained elusive. Here, we report the first case of a SMARCB1-deficient undifferentiated carcinoma in the rectum expressing high PD-L1 and responding to a PD-1 inhibitor, as well as wi...

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Main Authors: Wenjuan Shen (Author), Yi Pan (Author), Shuangmei Zou (Author)
Format: Book
Published: BMC, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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