The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity

• Egile Nagusiak: Andersson David A (Egilea), Stoakley Natalie (Egilea), Gentry Clive (Egilea), Bevan Stuart (Egilea)
• Formatua: Liburua
• Argitaratua: SAGE Publishing, 2010-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The cooling agents menthol and icilin act as agonists at TRPM8 and TRPA1. <it>In vitro</it>, activation of TRPM8 by icilin and cold, but not menthol, is dependent on the activity of a sub-type of phospholipase A2, iPLA2....