Interferon gamma-inducible protein 16 (IFI16) and anti-IFI16 antibodies in primary Sjögren's syndrome: findings in serum and minor salivary glands

• Main Authors: A. Alunno (Author), V. Caneparo (Author), F. Carubbi (Author), O. Bistoni (Author), S. Caterbi (Author), M. Gariglio (Author), E. Bartoloni (Author), S. Landolfo (Author), R. Gerli (Author)
• Format: Book
• Published: PAGEPress Publications, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The interferon (IFN) signature, namely the overexpression of IFN-inducible genes is a crucial aspect in the pathogenesis of primary Sjögren's syndrome (pSS). The IFN-inducible IFI16 protein, normally expressed in cell nuclei, may be overexpressed, mislocalized in the cytoplasm and secreted in...