IUPHAR Review - Bivalent and bifunctional opioid receptor ligands as novel analgesics

Though efficacious in managing chronic, severe pain, opioid analgesics are accompanied by significant adverse effects including constipation, tolerance, dependence, and respiratory depression. The life-threatening risks associated with µ opioid receptor agonist-based analgesics challenges their use...

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Bibliographic Details
Main Authors: Kyle J. Rehrauer (Author), Christopher W. Cunningham (Author)
Format: Book
Published: Elsevier, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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