Wogonin protects against bleomycin-induced mouse pulmonary fibrosis via the inhibition of CDK9/p53-mediated cell senescence

• Main Authors: Libo Wang (Author), Fei Lin (Author), Youli Liu (Author), Wei Li (Author), Qingjie Ding (Author), Xulei Duan (Author), Lin Yang (Author), Zhengyu Bai (Author), Min Zhang (Author), Yuming Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary fibrosis (PF) is a fatal interstitial lung disease associated with declining pulmonary function but currently with few effective drugs. Cellular senescence has been implicated in the pathogenesis of PF and could be a potential therapeutic target. Emerging evidence suggests wogonin, the bio...