Toll-Like Receptor 4 in Bone Marrow-Derived Cells Contributes to the Progression of Diabetic Retinopathy

• Hlavní autoři: Hui Wang (Autor), Haojun Shi (Autor), Jing Zhang (Autor), Guoliang Wang (Autor), Jinxiang Zhang (Autor), Fagang Jiang (Autor), Qing Xiao (Autor)
• Médium: Kniha
• Vydáno: Hindawi Limited, 2014-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Diabetic retinopathy (DR) is a major microvascular complication in diabetics, and its mechanism is not fully understood. Toll-like receptor 4 (TLR4) plays a pivotal role in the maintenance of the inflammatory state during DR, and the deletion of TLR4 eventually alleviates the diabetic inflammatory s...