Dual Inhibitors Targeting DNA and Histone Deacetylases

Histone deacetylases (HDACs) regulate the acetylation status of histones and structural status of chromatin. The chromatin structure becomes relaxed after inhibition of HDAC, leading to DNA exposed to DNA disrupting agents, and eventually causing DNA dysfunction. Recently, more and more dual inhibit...

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Váldodahkkit: Chen Chen (Dahkki), Xinying Yang (Dahkki), Xuben Hou (Dahkki), Hao Fang (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: Georg Thieme Verlag KG, 2020-06-01T00:00:00Z.
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